<p>In recent years, the theme of museums and virtual exhibitions has been the subject of a wide debate and a significant number of researches and experiments. In a vast and articulated framework of experiences, this article intends to highlight new strategies related to the creation of digital museum paths based on a multidisciplinary approach. The research presented here intends to create a protocol for the construction of digital museums based on the definition of an ontology capable of integrating digital elaborations of 3D virtual models and exhibition projects with semantic relationships. The experimentation conducted has considered, in particular, some issues concerning drawn architectures. Thanks to a rigorous methodological approach and the use of new technologies for virtual and augmented reality, it has been possible to build a tool that allows improving the knowledge of the cultural heritage investigated through the customizable structuring of virtual exhibitions. It is a tool that, thanks to its flexibility and precision, can satisfy the widest user target, ranging from experts (professionals, designers, historians, researchers, etc.) to simple visitors (tourists, enthusiasts, etc.).</p>