The purpose of this paper is to discuss how much the phases of flight planning and the setting of the camera orientation can affect a UAVs photogrammetric survey. The test site chosen for these evaluations was the Rocca of San Silvestro, a medieval monumental castle near Livorno, Tuscany (Italy). During the fieldwork, different sets of data have been acquired using different parameters for the camera orientation and for the set up of flight plans. Acquisition with both nadiral and oblique orientation of the camera have been performed, as well as flights with different direction of the flight lines (related with the shape of the object of the survey). The different datasets were then processed in several blocks using Pix4D software and the results of the processing were analysed and compared. Our aim was to evaluate how much the parameters described above can affect the generation of the final products of the survey, in particular the product chosen for this evaluation was the point cloud.