This paper describes a new framework for classification of hyperspectral images, based on both spectral and spatial information. The spatial information is obtained by an enhanced Marker-based Hierarchical Segmentation (MHS) algorithm. The hyperspectral data is first fed into the Multi-Layer Perceptron (MLP) neural network classification algorithm. Then, the MHS algorithm is applied in order to increase the accuracy of less-accurately classified land-cover types. In the proposed approach, the markers are extracted from the classification maps obtained by MLP and Support Vector Machines (SVM) classifiers. Experimental results on Washington DC Mall hyperspectral dataset, demonstrate the superiority of proposed approach compared to the MLP and the original MHS algorithms.