One of the main problems of rescue workers in confrontation of fired complex buildings is the lack of sufficient information about the building indoor environment and their emergency exit ways. Building information modeling (BIM) is a database for building a 3D model of building information to create a 3D building geometry network model. This paper has implemented some GIS and BIM integration analyses to determine the shortest and safest paths to people under fire risk and simulate their movement in the building. Plasco building was a multi-story shop in Tehran which has been fired in 2017 and destroyed. This paper attempts to simulate the firefighting and rescue operations in Plasco Building using an integration of BIM and GIS. There is no detailed information about the building and the fire incident, therefore the developed BIM and corresponding geometric network might differ slightly. The shortest and safest paths to the exit door or windows where the fire ladders are located are computed and analyzed. As a result of 15 scenarios developed in this paper, it was found that at 87% of the cases, the safest paths for the emergency exit of the people at risk were longer than the shortest paths. This study has evaluated different scenarios for the shortest and safest paths using Dijkstra algorithm considering different origins and destination points in the 3D indoor environment to assist the rescue operations.