Runoffs from hydrologic models are often used in flood models, among other applications. These runoffs are converted from rainfall, signifying the importance of weather data accuracy. A common challenge for modelers is local weather data sparsity in most watersheds. Global weather datasets are often used as alternative. This study investigates the statistical significance and accuracy between using local weather data for hydrologic models and using the Climate Forecast System Reanalysis (CFSR), a global weather dataset. The Soil and Water Assessment Tool (SWAT) was used to compare the two weather data inputs in terms of generated discharges. Both long-term and event-based results were investigated to compare the models against absolute discharge values. The basin’s average total annual rainfall from the CFSR-based model (4062 mm) was around 1.5 times the local weather-based model (2683 mm). These basin precipitations yielded annual average flows of 53.4 cms and 26.7 cms for CFSR-based and local weather-based models, respectively. For the event-based scenario, the dates Typhoon Ketsana passed through the Philippine Area of Responsibility were checked. CFSR only read a spatially averaged maximum daily rainfall of 18.8 mm while the local gauges recorded 157.2 mm. Calibration and validation of the models were done using the observed discharges in Sto. Niño Station. The calibration of local weather-based model yielded satisfactory results for the Nash-Sutcliffe Efficiency (NSE), percent of bias (PBIAS), and ratio of the RMSE to the standard deviation of measured data (RSR). Meanwhile, the calibration of CFSR model yielded unsatisfactory values for all three parameters.