The Amazon region is undergoing a dynamic and extensive transformation from forested areas to human-altered landscapes, significantly impacting forests and indigenous territories. This research aims to create future land use and land cover (LULC) scenarios by examining past trends (2014–2022) and predicting future patterns for 2030, focusing on the Kakataibo territory in central Peru. Using the Dinamica EGO modelling platform, we projected LULC changes based on historical data and various predictive factors. Our findings reveal notable forest loss between 2014 and 2022, with this trend likely continuing through 2030. Within indigenous territories, deforestation was less severe, with a reduction of 30,247.4 hectares compared to the more significant loss in non-indigenous areas. This underscores the vital role these territories play in mitigating forest loss. However, the rapid expansion of agriculture and infrastructure within these regions signals an urgent need for stronger legal protections to halt further deforestation. This study highlights the critical importance of indigenous territories in forest conservation and offers valuable insights for future land management and conservation strategies in the Amazon.