Remote Sensing-based change detection (CD) focuses on the identification of Earth's surface transformations through analysis of multi-temporal satellite images captured for the same geographic region at different points in time. Two common classification-based change detection techniques are post-classification comparison of land cover maps and direct classification of image differences between two periods of interest. In either approach, the selection of an appropriate classifier is critical. Consequently, this study focuses on assessing the performance of different classifiers, including the multi-layer perceptron neural network (MLPNN), support vector machine (SVM), random forest (RF), maximum likelihood (MLH), k-nearest neighbor (KNN), and gaussian naïve bayes (GNB). For this evaluation, two high resolution images captured in 2016 and 2020 by the PS2 sensor within the PlanetScope satellite constellation were used. Additionally, a novel unbiased sampling technique was introduced to selectively capture a minimal number of reference pixels. In the context of change detection, slight variations were observed in classification performance rankings between post-classification and difference image classification methods. However, a consistent trend emerged. The MLPNN consistently achieved the highest accuracy, closely followed by RF and SVM as the second or third-best performers in each technique. In contrast, GNB consistently yielded less favourable results. Importantly, our findings highlight the persistent superiority of the difference image classification in terms of change detection accuracy across all six classifiers. Furthermore, this method offers a significant advantage due to its reduced processing time and computational demands, positioning it as the preferred choice for binary change detection when compared to post-classification techniques.